Inference of Genotype-Molecular Phenotype-Clinical Phenotype Associations

Image credit: Cancer evolution: Darwin and beyond

Our research integrates genomic, molecular, and clinical data to infer the relationships between these different layers of tumor biology. We focus on identifying tumor biomarkers, understanding tumor evolution, and performing prognostic analysis, all of which are essential for early diagnosis, targeted therapy, and individualized patient prognosis.

Laboratory of Shanghai Center for Systems Biomedicine
Laboratory of Shanghai Center for Systems Biomedicine

Our research aims to utilize machine learning and artificial intelligence, combined with systems biology, to comprehensively characterize the genotypes, molecular phenotypes, and clinical phenotypes within the tumor microenvironment. Our goal is to explore the intricate relationships among these three aspects in order to contribute to the advancement of precision oncology.