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CRISPR
Model-based understanding of single-cell CRISPR screening
In summary, MUSIC provides an effective and applicable solution to elucidate perturbation function and biologic circuits by a model-based quantitative analysis of single-cell-based CRISPR screening data.
Bin Duan#
,
Chi Zhou
,
Chengyu Zhu
,
Yifei Yu
,
Shuyang Sun
,
Qi Liu
DOI
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MUSIC
MUSIC provides an effective and applicable solution to elucidate perturbation function and biologic circuits by a model-based quantitative analysis of single-cell-based CRISPR screening data.
Apr 20, 2019
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DeepCRISPR: optimized CRISPR guide RNA design by deep learning
In addition, DeepCRISPR fully automates the identification of sequence and epigenetic features that may affect sgRNA knockout efficacy in a data-driven manner.
Guohui Chuai#
,
Hanhui Ma#
,
Jifang Yan
,
Ming Chen
,
Nanfang Hong
,
Dongyu Xue
,
Chi Zhou
,
Chenyu Zhu
,
Ke Chen
,
Bin Duan
,
Jia Wei
,
Qi Liu
DOI
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